Yale New Haven Hospital

Department of Laboratory Medicine
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Human Herpesvirus-6 (HHV-6) by PCR, CSF

Lab Section: 



Lab Location: 

Main Lab

Test ID: 




Real-Time TaqMan PCR


Daily, Mon-Fri


1-3 days

Specimen Requirements: 

Collection: 1.0 mL CSF in a sterile tube
CSF Tube 4 also acceptable.
Pediatric volume: 0.5 mL.
Transport: CSF specimens must be promptly delivered to the laboratory.



Clinical Indications: Febrile seizures in young children; neurologic disease in severely compromised hosts.

Note: Chromosomal integration of HHV-6 occurs in 0.5-1% of the population and is associated with high levels of HHV-6 DNA in CSF and blood, without disease.

HHV-6 infection is universal in childhood, and persists for life. Rarely primary infections can be documented in adults. Reactivation can occur with immunosuppression and is usually is not associated with disease.

Reference Interval: 

Not Detected

CPT Code(s): 


Last Changed: 

8/22/2017 12:40:43 PM

Last Reviewed: 

8/22/2017 12:40:43 PM