Yale New Haven Hospital

Department of Laboratory Medicine
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Hypercoagulable panel

Lab Section: 

Coagulation

 

Lab Location: 

Main Lab

Test ID: 

LAB3137

 

Synonyms: 

HYPER

Methodology: 

Chromogenic; clotting

Schedule: 

2-3 times per week (two weeks cycle)

Reported: 

3 - 5 days

Specimen Requirements: 

Collection: 2.7 mL Blood in a Blue Top Tube.
Pediatric volume: 2.7 mL.
Three (3) full 2.7-mL blue top tubes are required for this work up.
Transport: Whole blood may be transported at ambient or refrigerated temperature. Separated plasma, not yet frozen, may be transported at refrigerated temperature, while frozen plasma should be sent on dry ice to prevent thawing in transit.
Unacceptable conditions: QNS; clotted; overfilled

 

Notes: 

Reflex Criteria: Hyper Coagulation panel auto reflex to PT/PTT. Low Protein S activity reflexes to Protein S Total and Free antigen tests. Abnormal results reflex to MD interpretation.

Clinical Indications: Evaluation of thrombosis risk.

Tests in this Panel: 

Test Name

Reference Interval

Protein S Functional [LRR15822]

Age Limit

Sex

Normal Range

0 - 1 Days

Any

30

45 %

2 Days - 5 Days

Any

35

65 %

6 Days - 5 Years

Any

65

135 %

6 Years - 10 Years

Any

65

155 %

11 Years - 15 Years

Any

65

140 %

15 Years - 999 Years

Any

50

120 %

APC resistance [LRR11359]

Age Limit

Sex

Normal Range

0 Days - 999 Years

Any

>=2.20

Protein C Activity [LRR15813]

Age Limit

Sex

Normal Range

0 - 1 Days

Any

15

55 %

2 Days - 1 Months

Any

20

65 %

1 Months - 3 Months

Any

30

80 %

4 Months - 6 Months

Any

35

80 %

7 Months - 5 Years

Any

40

90 %

6 Years - 10 Years

Any

45

95 %

11 Years - 15 Years

Any

55

110 %

15 Years - 999 Years

Any

70

140 %

Antithrombin Activity [LRR11959]

Age Limit

Sex

Normal Range

0 - 1 Days

Any

40

85 %

2 Days - 5 Days

Any

40

95 %

6 Days - 1 Months

Any

50

110 %

1 Months - 999 Years

Any

80

125 %

CPT Code(s): 

85300, 85303, 85306, 85307

Last Changed: 

8/18/2017 10:58 AM

Last Reviewed: 

8/18/2017 10:58 AM