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Sjogren's Antibodies (SS-A,SS-B)

Lab Section:  Immunology  
Lab Location:  Main Lab
Test ID: LAB3861 
Methodology: Enzyme-Linked Immunosorbent Assay
Schedule: Monday, Wednesday, Friday
Reported: 5 days
Specimen Requirements:  Collection: 5.0 mL Blood in a Gold Top Tube.
Pediatric volume: 1.0 mL.
Unacceptable conditions: Grossly hemolyzed specimens
Stability: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 6 months (avoid repeated freeze/thaw cycles)

Notes: 

Clinical Indications: SSA (Ro) antibody is seen in 70-75% of Sjögren syndrome cases, 30-40% of systemic lupus erythematosus (SLE), and 5-10% of progressive systemic sclerosis (PSS). SSB (La) antibody is seen in 50-60% of Sjögren syndrome cases. Fifteen-25% of patients with systemic lupus erythematosus (SLE) and 5-10% of patients with progressive systemic sclerosis (PSS) also have this antibody.

Reference Interval:  Reference Intervals: 
        <20 Units = Negative 
      20-39 Units = Weak Positive 
      40-80 Units = Moderate Positive 
        >80 Units = Strong Positive
Tests in this Panel: 
Test NameReference Interval
SS-A Sjogrens Ab [LRR16365]
Age Limit Sex Normal Range
0 Days - 999 Years Any <20 Units
SS-B Sjogrens Ab [LRR16367]
Age Limit Sex Normal Range
0 Days - 999 Years Any <20 Units
CPT Code(s): 86235
Last Changed: 01/05/2017 15:28:50
Last Reviewed: 01/05/2017 15:16:22