Yale New Haven Hospital

Department of Laboratory Medicine
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JC virus by PCR, CSF

Lab Section: 

Virology

 

Lab Location: 

Main Lab

Test ID: 

LAB4073

 

Synonyms: 

Polyomavirus JC PCR, CSF

Methodology: 

Real-Time TaqMan PCR

Schedule: 

Daily, Mon-Fri

Reported: 

1 day

Specimen Requirements: 

Collect Cerebrospinal Fluid in a Sterile Tube.
Pediatric volume: 0.5
Transport CSF specimens promptly to the laboratory..

 

Notes: 

Clinical Indications: Suspected or high risk for progressive multifocal leukoencephalopathy (PML). Highly sensitive NIH assay used.

JCV infection occurs in childhood and persists for life. Asymptomatic shedding occurs in urine. Detection in CSF usually correlates with PML. Definitive diagnosis requires biopsy. False negatives occur early in disease and with genome mutations.

Reference Interval: 

Not Detected

CPT Code(s): 

87798

Last Changed: 

8/24/2017 4:33:14 PM

Last Reviewed: 

8/24/2017 4:33:14 PM