Yale New Haven Hospital

Department of Laboratory Medicine
Test Directory

[ Test Name Index ]

[ Home & References ]

Beta-2 microglobulin, serum

Lab Section: 

Immunology

 

Lab Location: 

Main Lab

Test ID: 

LAB49

 

Methodology: 

Fluorescent enzyme immunoassay (FEIA)

Schedule: 

Monday-Friday

Reported: 

2 days

Specimen Requirements: 

Collection: 5.0 mL Blood in a Gold Top Tube.
Pediatric volume: 1 mL.
Unacceptable conditions: Grossly hemolyzed specimens
Stability: After separation from cells: Ambient 48 hours; Refrigerated: 7 days; Frozen: 60 days

 

Notes: 

Clinical Indications: Serum beta-2 microglobulin (B2M) levels are elevated in diseases associated with increased cell turnover. Levels are also elevated in several benign conditions such as chronic inflammation, liver disease, renal dysfunction, some acute viral infections, and a number of malignancies, especially hematologic malignancies associated with the B-lymphocyte lineage. In multiple myeloma, B2M is a prognostic factor.

Reference Interval: 

<2.65 mg/L

CPT Code(s): 

82232

Last Changed: 

11/21/2016 13:21:51

Last Reviewed: 

8/18/2017 2:12:00 PM