Yale New Haven Hospital

Department of Laboratory Medicine
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RPR

Lab Section: 

Virology

 

Lab Location: 

Main Lab

Test ID: 

LAB494

 

Synonyms: 

Rapid plasma reagin

Methodology: 

Semi-quantitative charcoal agglutination

Schedule: 

3 times a week

Reported: 

2- 4 days

Specimen Requirements: 

Collection: 3.0 mL Blood in a Gold Top Tube.
Pediatric volume: 1.0 mL
Unacceptable conditions: CSF or other body fluids

 

Notes: 

Clinical Indications: RPR is performed on all T. pallidum antibody screen positive samples to assess disease activity, and if positive, a titer is determined. False positive results can occur.

Nontreponemal tests for syphilis, such as RPR and VDRL, become reactive 4-6 weeks after infection with titers peaking during the secondary or early latent stage. Treatment in primary or secondary stages usually results in a rapid decline in titer. Treatment in late or latent stages has less effect on titers and the test may remain reactive at low titers indefinitely.

Reference Interval: 

Negative

CPT Code(s): 

86592

Last Changed: 

9/1/2017 3:42:27 PM

Last Reviewed: 

9/1/2017 3:42:27 PM