Yale New Haven Hospital

Department of Laboratory Medicine
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Deamidated gliadin peptide Ab, IgG

Lab Section: 

Immunology

 

Lab Location: 

Main Lab

Test ID: 

LAB6006

 

Methodology: 

Semi-Quantitative Chemiluminescent Immunoassay (CIA)

Schedule: 

Monday, Tuesday, Thursday

Reported: 

4 days

Specimen Requirements: 

Collection: 5.0 mL Blood in a Gold Top Tube.
Pediatric volume: 1 mL.
Unacceptable conditions: Grossly hemolyzed specimens.
Stability: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 6 months

 

Notes: 

Clinical Indications: Both gliadin IgA and IgG antibodies are detected in patients with Celiac disease or gluten sensitive enteropathy. Gliadin IgG antibodies seem more sensitive but are less specific markers for disease compared to IgA antibodies. Gliadin IgA antibodies are less sensitive but more specific. Although the IgA isotype of these antibodies usually predominates in celiac disease, individuals may also produce IgG isotypes, particularly if the individual is IgA deficient.

Reference Interval: 

<20 Units - Negative
20-30 Units - Weak Positive
>30 Units - Moderate to Strong Positive

CPT Code(s): 

83516

Last Changed: 

12/23/2016 14:56:12

Last Reviewed: 

8/16/2017 2:35:27 PM