Yale New Haven Hospital

Department of Laboratory Medicine
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Deamidated gliadin peptide Abs, IgA and IgG

Lab Section: 

Immunology

 

Lab Location: 

Main Lab

Test ID: 

LAB725

 

Methodology: 

Semi-Quantitative Chemiluminescent Immunoassay (CIA)

Schedule: 

Monday, Tuesday, Thursday

Reported: 

4 days

Specimen Requirements: 

Collection: 5.0 mL Blood in a Gold Top Tube.
Pediatric volume: 1 mL.
Unacceptable conditions: Grossly hemolyzed specimens.
Stability: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 6 months

 

Notes: 

Clinical Indications: Deaminated gliadin peptide antibodies have a sensitivity and specificity for celiac disease of 84% and 90-98% respectively. Persistence of antibodies after gluten withdrawal is usually indicative of low dietary compliance and lack of intestinal mucosal improvement. Combined use of these antibodies with tissue transglutamine antibodies (which has greater sensitivity) can be especially diagnostically useful.

Reference Interval: 

<20 CU = Negative
20-30 CU = Weak Positive
>30 CU = Positive

Tests in this Panel: 

Deamidated gliadin peptide Abs, IgA and IgG

Last Changed: 

12/23/2016 14:57:20

Last Reviewed: 

8/16/2017 2:34:14 PM