Yale New Haven Hospital

Department of Laboratory Medicine
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Scleroderma (Scl-70) Antibody

Lab Section: 

Immunology

 

Lab Location: 

Main Lab

Test ID: 

LAB771

 

Methodology: 

Enzyme-Linked Immunosorbent Assay

Schedule: 

Thursday

Reported: 

7 days

Specimen Requirements: 

Collection: 5.0 mL Blood in a Gold Top Tube.
Pediatric volume: 1.0 mL.
Unacceptable conditions: Grossly hemolyzed specimens.
Stability: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 6 months (avoid repeated freeze/thaw cycles)

 

Notes: 

Clinical Indications: Scleroderma (Scl-70) antibody is seen in 20-60% of patients with scleroderma and is considered diagnostic and specific for scleroderma.

Reference Interval: 

Reference Intervals: 
        <20 Units = Negative 
      20-39 Units = Weak Positive 
      40-80 Units = Moderate Positive 
        >80 Units = Strong Positive

CPT Code(s): 

86235

Last Changed: 

8/10/2017 3:33:09 PM

Last Reviewed: 

8/10/2017 3:33:16 PM