Yale New Haven Hospital

Department of Laboratory Medicine
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Buprenorphine Screen, Urine

Lab Section: 



Lab Location: 

Main Lab

Test ID: 






Enzyme Immunoassay


On request


1 hour for STAT orders; 4 hours for Routine orders

Specimen Requirements: 

Collection: 2.0 mL Urine in a Yellow Top Tube - Urine
Pediatric volume: 1.0 mL Urine.



Clinical Indications: Buprenorphrine is a pain medication, most often used in the treatment of narcotic addiction. This medication has the potential for misuse and/or diversion. Physicians who prescribe medications containing Buprenorphrine (Subutex, Suboxon) utilize this test to determine patient compliance with their prescriptions.

Reference Interval: 

Positive Results:

Any sample that gives a change in absorbance (A) value equal to or higher than CEDIA Buprenorphine II

Calibrator 10 ng/mL is interpreted as positive.


Negative Results:

Any sample that gives a change in abdorbance (A) value less than CEDIA Buprenorphine II Calibrator 10

ng/mLis interpreted as negative. Either the sample does not contain the drug being assayed or drug is

present in concentration below the cutoff level for this assay.

CPT Code(s): 


Last Changed: 

2/21/2018 13:53:47

Last Reviewed: 

2/21/2018 13:53:47