Yale New Haven Hospital

Department of Laboratory Medicine
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ssDNA antibody, IgG

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Test ID: 




Anti-SS DNA Antibody; Single-Stranded DNA Antibody; ssDNA Antibody


Semi-Quantitative Enzyme-Linked Immunosorbent Assay


Tuesday, Thursday, Saturday


10 days

Specimen Requirements: 

Collection: 3.0 mL Blood in a Gold Top Tube.
Pediatric volume: 1 mL.
Serum separator tube.
Transport: Refrgierated.
Unacceptable conditions: Plasma. Contaminated, hemolyzed, or severely lipemic specimens.
Stability: After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)


Note: The ssDNA antibody test detects ssDNA and some dsDNA antibodies.  As a result, patient samples should also be tested for dsDNA antibodies in order to more accurately determine the level of anti-ssDNA antibodies.  By calculating the ratio (ssDNA/dsDNA), a conclusion can be made as to the presence of ssDNA antibodies.  A ratio less than or equal to 1.0 indicates the absence of ssDNA antibodies.  A ratio greater than 1.0 indicates the presence of ssDNA antibodies.


Reference Interval: 

See patient report or consult reference laboratory website.



CPT Code(s): 


Last Changed: 

8/23/2017 4:00:03 PM

Last Reviewed: 

8/23/2017 4:00:11 PM