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Ehrlichia chaffeensis antibody, IgM

Lab Section:  Sendout Reference  
Lab Location:  Sendout
Reference Lab: ARUP 
Test ID: LAB2916 
Methodology: Semi-Quantitative Indirect Fluorescent Antibody
Schedule: Tuesday, Friday
Reported: 7 days
Specimen Requirements:  Collection: 3.0 mL Blood in a Gold Top Tube.
Pediatric volume: 1 mL.
Handling: Separate serum from cells ASAP. Acute and convalescent specimens must be labeled as such; parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Please mark specimen plainly as "acute" or "convalescent.".
Unacceptable conditions: Severely lipemic, contaminated, or hemolyzed specimens.
Stability: After separation from cells: Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Notes: 

Clinical Indications: Used to diagnose infection with Ehrlichia chaffeensis. IgM titers alone may not be sufficient to confirm disease. May require acute and convalescent samples to determine presence of disease.

Human ehrlichiosis is a tick-borne disease caused by rickettsial-like agents. Two forms, human monocytic ehrlichiosis (HME) and human granulocytic ehrlichiosis (HGE), have been described. HME is often referred to as "spotless" or rashless Rocky Mountain spotted fever, and has been reported in various regions of the United States. The causative agent of HME has been identified as Ehrlichia chaffeensis. Infected individuals produce specific antibodies to Ehrlichia chaffeensis which can be detected by an immunofluorescent antibody (IFA) test.

Reference Interval:  See patient report or consult reference laboratory website.
CPT Code(s): 86666
Last Changed: 11/16/2016 23:00:55
Last Reviewed: 12/21/2016 06:13:05