Yale New Haven Hospital

Department of Laboratory Medicine
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Iron, liver tissue

Lab Section: 

Sendout Reference

 

Lab Location: 

Sendout

Reference Lab: 

ARUP

 

Test ID: 

LAB3

 

Methodology: 

Quantitative Inductively Coupled Plasma-Mass Spectrometry

Schedule: 

Daily

Reported: 

10 days

Specimen Requirements: 

Collection: 1.0 mg Tissue in a Miscellaneous Container.
Pediatric volume: 0.25 mg.
Liver tissue obtained with an 18 gauge needle. Transport at least a 1 cm long specimen. Tissue can be fresh, paraffin-embedded, or dried. Also acceptable: Formalin-fixed. Specimens should be stored and transported in a metal-free container such as a royal blue (no additive).
Transport: Refrigerated.
Handling: Paraffin blocks are acceptable. Age is required on test request form in order to calculate iron index. Formalin is acceptable, but not preferred.
Unacceptable conditions: Specimens less than 0.25 mg (dry weight). Specimens stored or shipped in saline.
Stability: In paraffin block, preserved (formalin), or dried: Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Indefinitely. Fresh tissue: Ambient: Unacceptable; Refrigerated: 1 week; Frozen: Indefinitely

 

Notes: 

Clinical Indications: Useful in confirming hepatic iron overload, particularly in individuals with hemochromatosis and no common HFE mutations

Reference Interval: 

See patient report or consult reference laboratory website.

CPT Code(s): 

83540

Last Changed: 

11/11/2016 14:56:05

Last Reviewed: 

8/8/2017 11:07:21