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Immunoglobulin A subclasses (1 and 2)

Lab Section:  Sendout Reference  
Lab Location:  Sendout
Reference Lab: Quest 
Test ID: LAB3157 
Methodology: Nephelometry
Schedule: Tuesdays
Reported: 10 days
Specimen Requirements:  Collection: 4.0 mL Blood in a Gold Top Tube.
Pediatric volume: 2 mL.
Centrifuge and immediately separate serum specimens from the cells into clean, plastic screw-cap vial
Transport: Refrigerated (cold packs).
Unacceptable conditions: Received room temperature No additive (royal blue-top)
Stability: Room temperature: 6 hours Refrigerated: 14 days Frozen: 90 days


Clinical Indications: IgA1 constitutes approximately 80% of the circulating IgA. IgA nephropathy is typically due to IgA1. IgA2 predominates in secretions of some mucosal surfaces. IgA2 concentrations may be useful as an index of mucosal pathology. Subclass deficiency is associated with analyphylactic transfusion reactions.

Reference Interval:  See patient report or consult reference laboratory website.
CPT Code(s): 82784, 82787 (x2)
Last Changed: 11/11/2016 11:55:05
Last Reviewed: 12/27/2016 00:03:47