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Isopropanol solubility (unstable Hgb)

Lab Section:  Sendout Reference  
Lab Location:  Sendout
Reference Lab: Mayo 
Test ID: LAB3188 
Synonyms: Unstable hemoglobin
Methodology: Turbidimetric
Schedule: Monday through Friday; 10:30 a.m.
Reported: 7 - 14 days
Specimen Requirements:  Collection: 5.0 mL Blood in a Lavender Top Tube.
Pediatric volume: 1.0 mL.
Only orderable as part of a profile or as a reflex. Whole blood EDTA
Transport: Refrigerated.
Stability: Refrigerated up to 7 days


Clinical Indications: Unstable hemoglobin disease is rare and may be caused by any 1 of a large number of hemoglobin variants. They are inherited as an autosomal dominant trait. The severity of the disease varies according to the hemoglobin variant; there may be no clinical symptoms or the disease may produce a mild, moderate, or severe hemolytic anemia. The stained peripheral blood smear shows anisocytosis, poikilocytosis, basophilic stippling, polychromasia and, sometimes, hypochromia. The reticulocyte count may be increased. Splenomegaly and Heinz bodies may also be present.

Reference Interval:  See patient report or consult reference laboratory website.
CPT Code(s): 83068
Last Changed: 11/11/2016 15:04:52
Last Reviewed: 12/27/2016 00:07:44