Yale New Haven Hospital

Department of Laboratory Medicine
Test Directory

[ Test Name Index ]

[ Home & References ]

Orotic acid, urine

Lab Section: 

Sendout Reference

 

Lab Location: 

Sendout

Reference Lab: 

Mayo

 

Test ID: 

LAB3301

 

Methodology: 

Colorimetric

Schedule: 

Wednesday, 8am

Reported: 

15 days

Specimen Requirements: 

Collection: 10.0 mL Urine in a Yellow Top Tube - Urine.
Pediatric volume: 3 mL.
Plastic, 10-mL urine tube; No preservative; Patient's age is required
Transport: Frozen.
Stability: Frozen: 30 days

 

Notes: 

Clinical Indications: Evaluation of the differential diagnosis of hyperammonemia and hereditary orotic aciduria When orotic acid is measured after a protein load or administration of allopurinol, excretion of orotic acid is a very sensitive indicator of ornithine transcarbamylase (OTC) activity. An allopurinol challenge may be helpful in determining whether a female patient may be a carrier of an OTC mutation if molecular genetic testing was not informative.

Reference Interval: 

See patient report or consult reference laboratory website.

CPT Code(s): 

83921

Last Changed: 

11/22/2016 10:51:29

Last Reviewed: 

8/29/2017 5:50:22