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Estradiol

Lab Section:  Sendout Reference  
Lab Location:  Sendout
Reference Lab: Quest 
Test ID: LAB523 
Methodology: Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)
Schedule: Daily
Reported: 5 days for Routine orders
Specimen Requirements:  Collection: 3.0 mL Blood in a Red Top Tube.
Pediatric volume: 1 mL.
Unacceptable conditions: Received room temperature Serum separator tube Moderate to gross hemolysis Lipemia Animal specimen
Stability: Room temperature: 48 hours Refrigerated: 7 days Frozen: 2 years

Notes: 

Clinical Indications: Measuring the circulating levels of estradiol is important for assessing the ovarian function and monitoring follicular development for assisted reproduction protocols. Estradiol plays an essential role throughout the human menstrual cycle. Elevated estradiol levels in females may also result from primary or secondary ovarian hyperfunction. Very high estradiol levels are found during the induction of ovulation for assisted reproduction therapy or in pregnancy. Decreased estradiol levels in females may result from either lack of ovarian synthesis (primary ovarian hypofunction and menopause) or a lesion in the hypothalamus-pituitary axis (secondary ovarian hypofunction). Elevated estradiol levels in males may be due to increased aromatization of androgens, resulting in gynecomastia.

Reference Interval:  See patient report or consult reference laboratory website.
CPT Code(s): 82670
Last Changed: 12/26/2016 23:25:25
Last Reviewed: 12/26/2016 23:25:35