Yale New Haven Hospital

Department of Laboratory Medicine
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Soluble liver antigen (SLA) autoantibody

Lab Section: 

Sendout

 

Lab Location: 

Sendout

Reference Lab: 

Quest

 

Test ID: 

LAB5434

 

Methodology: 

Enzyme Linked Immunosorbent Immunoassay (ELISA)

Schedule: 

Wednesdays

Reported: 

14 days

Specimen Requirements: 

Collection: 3.0 mL Blood in a Gold Top Tube.
Pediatric volume: 1 mL.
Serum collected in a SST or red top tube
Transport: Refrigerated (cold packs).
Stability: Room Temperature: 48 hours; Refrigerated: 8 days Frozen: 4 weeks

 

Notes: 

Clinical Indications: Anti-soluble liver antigen antibodies are detected in 10-30% of patients with type 1 autoimmune hepatitis (AIH), but not in patients with type 2 AIH, primary sclerosing cholangitis or primary biliary cirrhosis. The antibody is directed against a UGA suppressor tRNA-associated protein. In some patients with AIH, this antibody may be the only autoantibody detected by current assays.

Reference Interval: 

See patient report or consult reference laboratory website.

CPT Code(s): 

83520

Last Changed: 

12/15/2016 10:35:59

Last Reviewed: 

12/27/2016 01:31:57