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Carbamazepine-10,11 epoxide

Lab Section:  Sendout Reference  
Lab Location:  Sendout
Reference Lab: Quest 
Test ID: LAB5456 
Methodology: Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)
Schedule: Monday-Fridays
Reported: 5 days for routine orders.
Specimen Requirements:  Collection: 4.0 mL Blood in a Red Top Tube.
Pediatric volume: 2.0 mL.
Unacceptable conditions: Serum separator tubes are unacceptable.
Stability: Am;bient: 14 days; Refrigerated: 14 days; Frozen: 10 months


Clinical Indications: Carbamazepine and its metabolite (10, 11-Carbamazepine epoxide) are widely used for control of generalized tonic-clonic, partial-onset, complex and mixed seizure disorders. The metabolism of carbamazepine in epileptic patients has several different pathways that can be altered when the patient is co-medicated with other anticonvulsants and, therefore, its therapeutic level should be monitored along with its metabolite in their free and protein bound states.

Reference Interval:  See patient report or consult reference laboratory website.
CPT Code(s): 82570 83789
Last Changed: 10/06/2016 14:47:51
Last Reviewed: 12/21/2016 05:32:27