Yale New Haven Hospital

Department of Laboratory Medicine
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Risperidone

Lab Section: 

Sendout Reference

 

Lab Location: 

Sendout

Reference Lab: 

Quest

 

Test ID: 

LAB5610

 

Methodology: 

Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)

Schedule: 

Tues, Thurs, Sat

Reported: 

14 days

Specimen Requirements: 

Collection: 5.0 mL Blood in a Red Top Tube.
Pediatric volume: 2 mL.
Transport: Room temperature.
Unacceptable conditions: Serum Separator Tube (SSTŪ)
Stability: Ambient: 7 days; Refrigerated: 28 days; Frozen: 60 days

 

Notes: 

Clinical Indications: Therapeutic drug monitoring for effective therapy. Risperidone is rapidly converted into its hydroxy metabolite in the liver. Peak concentration of risperidone occurs in about 1 hour following oral administration and for 9-hydroxyrisperidone the peak level is reached at 3 hours (17 hours for poor metabolizers). The elimination half-life of risperidone is 3 hours (20 hours for poor metabolizers), and is 21 hours of hydroxyrisperidone (30 hours for poor metabolizers).

Reference Interval: 

See patient report or consult reference laboratory website.

http://www.questdiagnostics.com/testcenter/TestDetail.action?tabName=OrderingInfo&ntc=2339

CPT Code(s): 

80342

Last Changed: 

8/24/2017 7:52:26 AM

Last Reviewed: 

8/24/2017 7:52:33 AM