Yale New Haven Hospital

Department of Laboratory Medicine
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NMDA receptor Ab, IgG w/reflex to titer

Lab Section: 

Sendout Reference


Lab Location: 


Reference Lab: 



Test ID: 




Glutamate Receptor Antibodies N-methyl-D-Aspartate Receptor Antibody, IgG


Semi-Quantitative Indirect Fluorescent Antibody


Tuesday, Friday


10 days

Specimen Requirements: 

Collection: 3.0 mL Blood in a Gold Top Tube.
Pediatric volume: 1 mL.
Serum separator tube.
Transport: Refrigerated.
Unacceptable conditions: CSF or plasma. Contaminated, hemolyzed, or severely lipemic specimens.
Stability: After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)



Clinical Indications: Anti-NMDA receptor IgG antibody is found in a subset of patients with autoimmune limbic encephalitis and may occur with or without associated tumor. Decreasing antibody levels may be associated with therapeutic response; therefore, clinical correlation must be strongly considered. A negative test result does not rule out a diagnosis of autoimmune limbic encephalitis.

Reference Interval: 

See patient report or consult reference laboratory website.


CPT Code(s): 

86255; if reflexed, add 86256

Last Changed: 

11/22/2016 10:01:43

Last Reviewed: 

8/28/2017 7:36:47