Yale New Haven Hospital

Department of Laboratory Medicine
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Nicotine and cotinine, LC/MS/MS, urine

Lab Section: 

Sendout Reference

 

Lab Location: 

Sendout

Reference Lab: 

Quest

 

Test ID: 

LAB7318

 

Methodology: 

Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)

Schedule: 

Daily

Reported: 

7 days

Specimen Requirements: 

Collection: 3.0 mL Urine in a Yellow Top Tube - Urine.
Pediatric volume: 1 mL.
Transport: Refrigerated (cold packs).
Stability: Ambient: 72 hours; Refrigerated: 14 days; Frozen: 30 days

 

Notes: 

Clinical Indications: This assay is used for the detection of nicotine and cotinine in urine to determine the tobacco exposure status of the individual. Nicotine has a short half-life of approximately forty minutes; Its presence may indicate recent tobacco exposure. Cotinine, the major nicotine metabolite, has a half-life of 24 hours and is detectable for several days after cessation of tobacco exposure.

Reference Interval: 

See patient report or consult reference laboratory website.

CPT Code(s): 

80323

Last Changed: 

11/22/2016 09:38:20

Last Reviewed: 

8/28/2017 7:25:05