Yale New Haven Hospital

Department of Laboratory Medicine
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Thyroid stimulating immunoglobulin

Lab Section: 

Sendout Reference

 

Lab Location: 

Sendout

Reference Lab: 

Quest

 

Test ID: 

LAB746

 

Synonyms: 

TSI

Methodology: 

In Vitro Bioassay

Schedule: 

Daily

Reported: 

7 days

Specimen Requirements: 

Collection: 3.0 mL Blood in a Red-top tube.
Pediatric volume: 1 mL.
Unacceptable conditions: Grossly lipemic • Received room temperature • Grossly icteric
Stability: Room temperature: Unacceptable Refrigerated: 21 days Frozen: 60 days


Notes: 

Clinical Indications: Graves' disease is a classic form of hyperthyroid disease, affecting approximately 0.4% of the population of the United States. It is caused by IgG immunoglobulins, collectively known as thyroid stimulating immunoglobulins (TSI). Patients who are candidates for antithyroid drug therapy may not respond to this treatment when TSI levels are markedly elevated. The determination of TSI can also assist in predicting hyperthyroidism in neonates, due to placental transmission of the immunoglobulins from a mother with hyperthyroidism.

Reference Interval: 

See patient report or consult reference laboratory website.

http://www.questdiagnostics.com/testcenter/BUOrderInfo.action?tc=30551&labCode=AMD

CPT Code(s): 

84445

Last Changed: 

8/16/2017 5:41:22

Last Reviewed: 

8/16/2017 5:41:22