Yale New Haven Hospital

Department of Laboratory Medicine
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Toll like receptor function

Lab Section: 

Sendout Reference

 

Lab Location: 

Sendout

Reference Lab: 

ARUP

 

Test ID: 

LAB7681

 

Synonyms: 

TLR Function

Methodology: 

Cell Culture/Quantitative Multiplex Bead Assay

Schedule: 

Daily

Reported: 

14 days

Specimen Requirements: 

Collection: 10.0 mL Green (sodium heparin)
Pediatric volume: 7 mL.
Green (sodium heparin) (patient) AND green (sodium heparin) (control). Also acceptable: Yellow (ACD solution A) (patient) AND yellow (ACD solution A) (control). Patient and control specimens must be collected within 48 hours of test performance.
Transport: CRITICAL: ROOM TEMPERATURE.
Handling: *STAT PICK UP* Collect control specimen from a healthy individual unrelated to patient at approximately the same time as and under similar conditions to the patient. Transport 10 mL whole blood (patient) AND 10 mL whole blood (control) in original collection tubes. (Min: 7 mL (patient) AND 7 mL (control)) Do not refrigerate or freeze. LIVE CELLS REQUIRED. Infant Minimum: 3 mL whole blood (patient) AND 7 mL whole blood (control).
Unacceptable conditions: Yellow (ACD Solution B). Refrigerated or frozen specimens.
Stability: Ambient: 48 hours; Refrigerated: Unacceptable; Frozen: Unacceptable

 

Notes: 

Clinical Indications: Assist in diagnosis of innate immunodeficiencies when genetic defects of the innate immune system are suspected in individuals negative for other immunodeficiencies (eg, no detectable abnormality of antibody function, complement activity, neutrophil function, or cell mediated immunity).

Reference Interval: 

See patient report or consult reference laboratory website.

CPT Code(s): 

83520x6, 86353x3

Last Changed: 

12/27/2016 03:01:56

Last Reviewed: 

8/16/2017 6:10:15